
The author explains the nature, reason and practical implications of determining the International Normalized Ratio (INR) for all clinicians and technical personnel, mainly those who work in laboratories. An exhaustive revision is made of the studies performed by the centres involved in thromboplastin calibration exercises to obtain the International Sensitivity Index (ISI) values.
Reference Values, International Cooperation, Calibration, Humans, Diagnostic Errors, Laboratories, World Health Organization, Liver Failure, Selection Bias, Thromboplastin
Reference Values, International Cooperation, Calibration, Humans, Diagnostic Errors, Laboratories, World Health Organization, Liver Failure, Selection Bias, Thromboplastin
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