Pentoxifylline and skin inflammation.

I, Bruynzeel; T J, Stoof; R, Willemze

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Clinical and Experim...arrow_drop_down

Clinical and Experimental Dermatology

Article . 1999

Data sources: Europe PubMed Central

Pentoxifylline and skin inflammation.

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1999 English Journal:Clinical and experimental dermatology, volume 23 (issn: 0307-6938,

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Authors: I, Bruynzeel; T J, Stoof; R, Willemze;

pmid: 9894361

Pentoxifylline and skin inflammation.

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Abstract

Cyclic nucleotide phosphodiesterase inhibitors, such as pentoxifylline, have been shown to beneficially influence a large number of inflammatory skin diseases. The biological effects of pentoxifylline on the production of proinflammatory cytokines, leukocyte-endothelial cell adhesion, chemokines and leukocyte-keratinocyte adhesion in skin inflammation are discussed.

Keywords

Phosphodiesterase Inhibitors, Cell Adhesion, Cytokines, Humans, Dermatitis, Pentoxifylline

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