Bed-wetting--primary nocturnal enuresis (PNE)--is a common yet misunderstood and under-treated childhood condition. PNE is both psychologically and physically distressing. Since bed-wetting children will often avoid peer activities for fear of overnight invitations, any child who avoids social situations and withdraws from most activities should be screened for PNE. Early screening and treatment can afford bed-wetters improved quality of life. School nurses are in an ideal position to identify potential enuretics. Given the range of available treatments, it is incumbent upon nurses to screen and advocate early treatment for these children.