[Antigenic activity of delta-antigen peptides corresponding to three genotypes of the delta hepatitis virus].
Copyright policy )[Antigenic activity of delta-antigen peptides corresponding to three genotypes of the delta hepatitis virus].
Six synthetic peptides from immunodominant region 65-80 aa derived from the sequences of delta-antigen corresponding to 3 HDV genotypes were obtained. Their antigenic activities were assessed by indirect enzyme immunoassay with sera of patients with hepatitis D and of asymptomatic carriers of anti-delta antibodies. Differences in antigenic characteristics of full-size 65-80 and truncated 71-80 aa peptides corresponding to three HDV genotypes were revealed. The diagnostic significance of synthetic 65-80 aa fragments is shown.
Hepatitis delta Antigens, Genotype, Molecular Sequence Data, Hepatitis Antigens, Antibodies, Viral, Hepatitis D, Peptide Fragments, Immunoenzyme Techniques, Carrier State, Humans, Amino Acid Sequence, Hepatitis Delta Virus
Hepatitis delta Antigens, Genotype, Molecular Sequence Data, Hepatitis Antigens, Antibodies, Viral, Hepatitis D, Peptide Fragments, Immunoenzyme Techniques, Carrier State, Humans, Amino Acid Sequence, Hepatitis Delta Virus
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