ADP-ribosylation factors in rat parotid acinar cells.
Copyright policy )ADP-ribosylation factors in rat parotid acinar cells.
ADP-ribosylation factor (Arf) is a 20 kDa polypeptide that is a member of the Ras superfamily of small molecular mass GTP-binding proteins. In addition to an essential role of Arf1 in vesicle budding, recent observations suggest a role for Arf6 in calcium-dependent exocytosis in bovine adrenal chromaffin cells. In rat parotid acinar cells, exocytosis is cAMP-dependent and our findings suggest an interaction of Arf1 with the secretory granules. We describe here the structural and functional background to the Arf proteins focusing on their role in rat parotid acinar cells.
- Nihon University Japan
Adenosine Diphosphate, ADP-Ribosylation Factors, GTP-Binding Proteins, Animals, Parotid Gland, ADP-Ribosylation Factor 1, Exocytosis, Rats
Adenosine Diphosphate, ADP-Ribosylation Factors, GTP-Binding Proteins, Animals, Parotid Gland, ADP-Ribosylation Factor 1, Exocytosis, Rats
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