
Desmoplastic neurotropic melanoma represents a rare histologic variant of malignant melanoma that is characterized by a proliferation of spindle cells in a densely collagenous stroma with pronounced neurotropism. A 60-year-old man appeared for evaluation of a mass in the lower lip. The labial mucosa was intact, and the lesion had been present for 2 months. The tumor was surgically removed, and after immunohistochemical and ultrastructural analysis it was diagnosed as desmoplastic neurotropic melanoma. The tumor recurred 6 months later, with involvement of the inferior alveolar nerve.
Male, Mandibular Nerve, Lip Neoplasms, Humans, Cranial Nerve Neoplasms, Neoplasm Invasiveness, Middle Aged, Neoplasm Recurrence, Local, Immunohistochemistry, Melanoma
Male, Mandibular Nerve, Lip Neoplasms, Humans, Cranial Nerve Neoplasms, Neoplasm Invasiveness, Middle Aged, Neoplasm Recurrence, Local, Immunohistochemistry, Melanoma
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