
This study aimed at evaluating MTC-sensitivity of frequently used MR-sequences.7 sequences (T1-, T2-, PD-weighted SE, four gradient-echo sequences) were combined with a 4 element on-resonance MT-Pulse at 0.5 Tesla (T5, Philips medical systems). The measurements were performed at a knee joint and MT-ratios of cartilage, muscle, fat and a copper sulfate phantom were calculated.Proton density weighted gradient and to a lesser degree spin-echo sequences were superior to T1- and T2-weighted sequences in visualising the MT effects.It is important to choose an appropriate MR-sequence for MTC experiments. Proton-density gradient echo sequences are recommended for that purpose. T1- and T2-weighted SE sequences should be avoided.
Cartilage, Articular, Copper Sulfate, Adipose Tissue, Knee Joint, Phantoms, Imaging, Humans, Reproducibility of Results, Muscle, Skeletal, Magnetic Resonance Imaging, Sensitivity and Specificity
Cartilage, Articular, Copper Sulfate, Adipose Tissue, Knee Joint, Phantoms, Imaging, Humans, Reproducibility of Results, Muscle, Skeletal, Magnetic Resonance Imaging, Sensitivity and Specificity
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