The dynamics of the populations of S. minnesota S- and R-forms in autolysis, induced by multifactor methods with and without the use of oleic acid, the analog of autolysis-activating autoregulator, was studied. In the process of autolysis the optical density (OD) of cell suspension, the total number of bacteria, the number of anabiotic refractile cells and the number of colony-forming units (CFU) were analyzed. The comparative analysis of the kinetics of the induced autolysis of Salmonella S- and R-forms was carried out, the phases of autolysis kinetics were determined. In the course of 1 hour following the induction of the autolysis of Salmonella S- and R-forms the paradoxical increase of the total number of bacteria and a sharp rise in the number of refractive anabiotic cells were observed simultaneously with the decrease of the OD of cell suspension and a sharp drop in the number of CFU; on hours 1-24 OP stabilized, the number of CFU increased, the total number of bacteria and the number of refractile cells decreased; on hours 24-48, simultaneously with the stabilization of the OD of cell suspension, the total number of salmonellae and the number of refractile anabiotic cells increased. The results thus obtained are indicative of the self regulation of Salmonella populations in induced autolysis and the necessity of controlling the process.