Treatment in patients with glioblastoma multiforme and poor performance status: is it worthwhile?

F L, Ampil; A, Nanda; B K, Willis; S, Apple

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Radiation Medicinearrow_drop_down

Radiation Medicine

Article . 1998

Data sources: Europe PubMed Central

Treatment in patients with glioblastoma multiforme and poor performance status: is it worthwhile?

descriptionPublicationkeyboard_double_arrow_right Article 03 Sep 1998 English Journal:Radiation medicine, volume 16 (issn: 0288-2043,

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Authors: F L, Ampil; A, Nanda; B K, Willis; S, Apple;

pmid: 9650897

Treatment in patients with glioblastoma multiforme and poor performance status: is it worthwhile?

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Abstract

It has not been ascertained that treatment of glioblastoma multiforme of the brain (GMB) favorably alters the prognosis in patients with poor pretreatment performance status (PPS). We report on 52 patients with GMB and PPS. The mean survival of 43 treated persons was 19 +/- 12 months (95% confidence interval) and of nine untreated individuals, 2 +/- 1 months (p > 0.50); the corresponding survival rates at 1 year were 39 +/- 16% and 0% (p > 0.05) and at 2 years, 15 +/- 12% and 0% (p > 0.40). We recommend active treatment of patients with GMB even when they present with poor functional status.

Related Organizations

University Medical Center
United States

Keywords

Male, Brain Neoplasms, Middle Aged, Combined Modality Therapy, Survival Rate, Treatment Outcome, Humans, Female, Karnofsky Performance Status, Neoplasm Recurrence, Local, Glioblastoma, Tomography, X-Ray Computed, Aged, Follow-Up Studies, Retrospective Studies

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