[Soluble IL-6 receptors].

E, Jabłońska

Found an issue? Give us feedback

Postępy Higieny i Me...arrow_drop_down

Postępy Higieny i Medycyny Doświadczalnej

Article . 1998

Data sources: Europe PubMed Central

[Soluble IL-6 receptors].

descriptionPublicationkeyboard_double_arrow_right Article 28 Jul 1998 Polish Journal:Postepy higieny i medycyny doswiadczalnej, volume 52 (issn: 0032-5449,

Copyright policy )

Authors: E, Jabłońska;

pmid: 9640977

[Soluble IL-6 receptors].

- Summary
- Subjects
- Metrics

Abstract

Both subunits of IL-6 membrane--associated receptor, IL-6R and gp130 can exhibit in a soluble forms--sIL-6R and sgp130 respectively. Soluble IL-6 receptor (sIL-6R) can bind IL-6 and mediate IL-6 function through association with gp130 which is the signal transducing protein. In contrast to other receptors, sIL-6R has a potential to enhance the IL-6 biological function. sIL-6R and sgp130 were found in appreciable amounts in body fluids, although the exact cellular source and function of these proteins are not completely clear.

Keywords

Membrane Glycoproteins, Antigens, CD, Cytokine Receptor gp130, Animals, Humans, Receptors, Interleukin-6, Body Fluids, Signal Transduction, Up-Regulation

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	0
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average