Ageing, nutritional status and immune response.
Copyright policy )Ageing, nutritional status and immune response.
The effects of vitamin supplementation on the age-related decline in immune function was studied in a population of elderly subjects with a high prevalence of low and deficient serum values of vitamin C, vitamin E, riboflavin and pyridoxin, as well as iron and zinc. The immune function was examined by measuring delayed cutaneous hypersensitivity (DCH) after intradermal application of a set of 7 antigens in 72 subjects aged 60-89 years living in two homes for the elderly. The results showed an almost linear statistically significant decline in the DCH test with age (p 0.05). No statistically significant changes in DCH were observed in the placebo group. The results of this study suggest that nutrition may be an important determinant of immunocompetence in the elderly.
- Institute of Public Health Zadar Croatia
Aged, 80 and over, Male, Aging, Immunity, ageing; vitamin supplementation; immunocompetence, Nutritional Status, Iron Deficiencies, Vitamins, Middle Aged, Body Mass Index, Zinc, Riboflavin Deficiency, Ascorbic Acid Deficiency, Humans, Female, Hypersensitivity, Delayed, Vitamin E Deficiency, Vitamin B 6 Deficiency, Aged
Aged, 80 and over, Male, Aging, Immunity, ageing; vitamin supplementation; immunocompetence, Nutritional Status, Iron Deficiencies, Vitamins, Middle Aged, Body Mass Index, Zinc, Riboflavin Deficiency, Ascorbic Acid Deficiency, Humans, Female, Hypersensitivity, Delayed, Vitamin E Deficiency, Vitamin B 6 Deficiency, Aged
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