Exhausted subjects, exhausted systems.

A, Appels

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Article . 1998

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Exhausted subjects, exhausted systems.

descriptionPublicationkeyboard_double_arrow_right Article 05 Feb 1998 English Journal:Acta physiologica Scandinavica. Supplementum, volume 640 (issn: 0302-2994,

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Authors: A, Appels;

pmid: 9401630

Exhausted subjects, exhausted systems.

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Abstract

A state of 'vital exhaustion', characterized by unusual tiredness, increased irritability and feelings of demoralization has been found to preceed the onset of myocardial infarction and to increase the risk of a new coronary event after angioplasty. Probably this state reflects a decreased activity of the hypothalamic-pituitary-adrenal axis as part of an homeostatic reaction to prolonged stress and inflammation.

Related Organizations

Maastricht University
Netherlands

Keywords

Adult, Male, Myocardial Infarction, Humans, Middle Aged, Fatigue, Aged

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