[APC, beta-catenin, DLG].
Copyright policy )[APC, beta-catenin, DLG].
The APC gene is mutated in the majority of colorectal tumors. The product of this gene is a 300 kDa protein associated with beta-catenin and the human homolog of the Drosophila tumor suppressor DLG. The study of the function of APC provides important insights into the mechanisms of the development of colorectal tumor.
- Osaka University Japan
Adenomatous Polyposis Coli Protein, Cell Cycle, Membrane Proteins, Proteins, Discs Large Homolog 1 Protein, Cytoskeletal Proteins, Mice, Adenomatous Polyposis Coli, Trans-Activators, Animals, Chromosomes, Human, Pair 5, Humans, Guanylate Kinases, beta Catenin, Adaptor Proteins, Signal Transducing
Adenomatous Polyposis Coli Protein, Cell Cycle, Membrane Proteins, Proteins, Discs Large Homolog 1 Protein, Cytoskeletal Proteins, Mice, Adenomatous Polyposis Coli, Trans-Activators, Animals, Chromosomes, Human, Pair 5, Humans, Guanylate Kinases, beta Catenin, Adaptor Proteins, Signal Transducing
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