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[The effect of mexidol on thymus cells in chronic hypokinesia].

Authors: O M, Vazhnycha; T O, Dev'iatkina; E H, Kovalenko;

[The effect of mexidol on thymus cells in chronic hypokinesia].

Abstract

The dynamic of mexidol's (3-oxipyridine derivate) influence on rats' thymic cells was studied under the conditions of 30-days hypokinesia. It was shown, that changes of thymic cells' content under the chronic hypokinesia developed in some stages. The prevent administration of mexidol (100 mg/kg of body weight) modified the lymphoid cells' migration. The remedy's effects on quantitative parameters of thymic cell's populations depended on stress stage and were synergic to natural adaptive processes. The most expressed mexidol's normalizing effect on thymic cells was marked on the 30th day of hypokinesia.

Keywords

Male, Psychotropic Drugs, Blood Cells, Time Factors, Bone Marrow Cells, Hypokinesia, Thymus Gland, Rats, Bone Marrow, Cell Movement, Chronic Disease, Picolines, Animals, Spleen

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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