[A family with hereditary hypofibrinogenemia].
Copyright policy )[A family with hereditary hypofibrinogenemia].
A family with congenital hypofibrinogenemia (fibrinogen levels of 60-90 mg%) has been studied. Out of 19 members tested, 11 exhibit this trait, which follows a strictly autosomal-dominant pattern of inheritance. Congenital hypofibrinogenemia appears to be a separate entity which can be distinguished from heterozygous individuals of congenital afibrinogenemia and from congenital dysfibrinogenemia. A bleeding tendency of clinical significance is observed only during major surgery or after severe injury.
Adult, Chromosome Aberrations, Male, Adolescent, Chromosome Disorders, Middle Aged, Afibrinogenemia, Obstetric Labor Complications, Pedigree, Postoperative Complications, Pregnancy, Humans, Blood Transfusion, Female, Uterine Hemorrhage, Child
Adult, Chromosome Aberrations, Male, Adolescent, Chromosome Disorders, Middle Aged, Afibrinogenemia, Obstetric Labor Complications, Pedigree, Postoperative Complications, Pregnancy, Humans, Blood Transfusion, Female, Uterine Hemorrhage, Child
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