A clinico-morphological analysis of two observations of cryptococcomas of the lungs are presented. In one case the diagnosis was established on the basis of cytological examinations of the sputum. This form of pulmonary cryptococcosis as well as identification of cryptococci in the sputum by cytological examinations are first described in the Soviet literature. The attention is drawn to the difficulties of clinico-roentgenological and morphological diagnosis of this disease and to the necessity to differentiate it from metastases of hyperneophroma, diseases of parasitic origin, and mycoses by other fungi.