[Determination of free PSA in 85 consecutive cases with increased total PSA].
Copyright policy )[Determination of free PSA in 85 consecutive cases with increased total PSA].
With a view to a more clearcut discrimination between benign prostatic hyperplasia (BPH) and prostate cancer (PCA), an additional measurement of the free PSA serum concentration and its ratio to total PSA (f-PSA/t-PSA) were determined in sera from 85 consecutive ambulatory patients with a total PSA concentration exceeding 4 ng/ml. Results with a ratio higher than 0.16 correlated with a high probability of benign disease (BPH), while a ratio below 0.16 was less meaningful. Thus, testing of free PSA seems to contribute to reducing the number of unnecessary biopsies in patients with elevated PSA.
Diagnosis, Differential, Male, Prostatic Hyperplasia, Humans, Prostatic Neoplasms, Prostate-Specific Antigen
Diagnosis, Differential, Male, Prostatic Hyperplasia, Humans, Prostatic Neoplasms, Prostate-Specific Antigen
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