
pmid: 8914131
handle: 11386/3104464 , 11591/230403
Ciprofloxacin susceptibility was evaluated in 573 clinical staphylococcal isolates (Staphylococcus aureus 230, methicillin-resistant (MR) 36%; coagulase-negative strains 343, MR 66%) collected from 1989 to 1995. Resistance to ciprofloxacin for MR Staphylococcus aureus was 25% until 1991 when ciprofloxacin was introduced into the hospital formulary, and rose progressively to 90% in 1994-1995. MR Staphylococcus haemolyticus showed a ciprofloxacin resistance of 46% until 1991 and of 73% from 1992 to 1995. In contrast MR Staphylococcus epidermidis and other coagulase-negative strains showed a constant susceptibility to this agent (80%). Ciprofloxacin has limited usefulness against MR Staphylococcus aureus but can be still used to treat Staphylococcus epidermidis infections.
Coagulase, Cross Infection, Staphylococcus aureus, Time Factors, Staphylococcus, Drug Resistance, Microbial, Staphylococcal Infections, Italy, Ciprofloxacin, Staphylococcus epidermidis, Humans, Methicillin Resistance
Coagulase, Cross Infection, Staphylococcus aureus, Time Factors, Staphylococcus, Drug Resistance, Microbial, Staphylococcal Infections, Italy, Ciprofloxacin, Staphylococcus epidermidis, Humans, Methicillin Resistance
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