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Different susceptibility of coagulase-positive and coagulase-negative staphylococci to ciprofloxacin.

Authors: UTILI, Riccardo; TRIPODI MF; ROSARIO P; ANDREANA A; LOCATELLI A; RAMBALDI A; FLORIO A.;

Different susceptibility of coagulase-positive and coagulase-negative staphylococci to ciprofloxacin.

Abstract

Ciprofloxacin susceptibility was evaluated in 573 clinical staphylococcal isolates (Staphylococcus aureus 230, methicillin-resistant (MR) 36%; coagulase-negative strains 343, MR 66%) collected from 1989 to 1995. Resistance to ciprofloxacin for MR Staphylococcus aureus was 25% until 1991 when ciprofloxacin was introduced into the hospital formulary, and rose progressively to 90% in 1994-1995. MR Staphylococcus haemolyticus showed a ciprofloxacin resistance of 46% until 1991 and of 73% from 1992 to 1995. In contrast MR Staphylococcus epidermidis and other coagulase-negative strains showed a constant susceptibility to this agent (80%). Ciprofloxacin has limited usefulness against MR Staphylococcus aureus but can be still used to treat Staphylococcus epidermidis infections.

Country
Italy
Keywords

Coagulase, Cross Infection, Staphylococcus aureus, Time Factors, Staphylococcus, Drug Resistance, Microbial, Staphylococcal Infections, Italy, Ciprofloxacin, Staphylococcus epidermidis, Humans, Methicillin Resistance

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
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