In this work the Authors show their own operative technique, attained in the surgical treatment of the neoplasms of the vestibule of the mouth. This operative technique also shows the possibility of reducing two surgical treatments to one. In other words it is possible to remove the primitive lesion and carry out, at the same time, the emptiness of those lymphonodulos chains the lymphtic vessels of the region are tributary to. In such a way the time elapsed between the operation and the following nuclear therapy is considerably reduced. Besides, though the exeresis implies an aesthetical injury, not considerable anyway, no functional deficiencies are shown since all the mouth functions, mastication, phonation, language, deglutition etc. are promptly recovered.