
Chlorcholine chloride (CCC) the molecule of which has no other group, characteristic of acetylcholine (Ach), causes an effective cholinomimetic action on the surface membrane of the mollusc neurons A and B. As the concentration of Ach and CCC increases from 10(-6) to 10(-3) M the resting potential (RP) and the membrane resistance (R) of the neuron A first increases then decreases. The increase of Ach and CCC concentration causes in the neuron B only a decrease of the above mentioned parameters. The data point to the necessity of improving the ideas about the structure of cholinoreceptors and mechanism of cholinoreceptor-cholinomimetic interaction.
Neurons, Mollusca, Electric Conductivity, Animals, Receptors, Cholinergic, Acetylcholine, Choline, Membrane Potentials
Neurons, Mollusca, Electric Conductivity, Animals, Receptors, Cholinergic, Acetylcholine, Choline, Membrane Potentials
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