Parasympathomimetic effects of mono sodium glutamate.
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The effects of Mono sodium glutamate on smooth muscles were studied using the guinea-pig isolated ileum. Mono sodium glutamate produced spasmogenic effect. Atropine blocked the contractile response elicited by Mono sodium glutamate whereas mepyramine and hexamethonium failed to do so. These findings suggest a cholinergic involvement at post ganglionic site of action.
Atropine, Pyrilamine, Guinea Pigs, Muscle, Smooth, Hexamethonium Compounds, In Vitro Techniques, Stimulation, Chemical, Rats, Glutamates, Parasympathomimetics, Ileum, Sodium Glutamate, Animals, Muscle Contraction
Atropine, Pyrilamine, Guinea Pigs, Muscle, Smooth, Hexamethonium Compounds, In Vitro Techniques, Stimulation, Chemical, Rats, Glutamates, Parasympathomimetics, Ileum, Sodium Glutamate, Animals, Muscle Contraction
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