
The argyrophilic nucleolar organizer regions (Ag-NORs) was measured in the tissue sample aspirated with fine needle for 17 cases of breast benign lesion and 46 cases of breast cancer, by analysis of their micro-image with light microscope and computed. The results indicated that the amount of Ag-NORs in the nuclei of breast cancer was increased while the percentage of average areas occupied by Ag-NORs was decreased. It was significant statistically in comparing with benign lesion (P 0.05). However the percentage of average areas occupied by Ag-NORs was different statistically (P < 0.05). The conclusion of Ag-NORs is of benefit to distinguish from benign and malignant tumours of breast as well as significant for evaluating the prognosis for breast cancer.
Adenoma, Diagnosis, Differential, Carcinoma, Ductal, Breast, Nucleolus Organizer Region, Humans, Nuclear Proteins, Antigens, Nuclear, Breast Neoplasms, Female, Prognosis
Adenoma, Diagnosis, Differential, Carcinoma, Ductal, Breast, Nucleolus Organizer Region, Humans, Nuclear Proteins, Antigens, Nuclear, Breast Neoplasms, Female, Prognosis
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