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Lysosomal glycolipid storage in the renal tubular epithelium in mastomys (Praomys coucha).

Authors: Fujimura, H.; Ogura, A.; Asano, T.; Noguchi, Y.; Mochida, K.; Takimoto, K.;

Lysosomal glycolipid storage in the renal tubular epithelium in mastomys (Praomys coucha).

Abstract

The renal proximal tubular epithelium of MCC strain of mastomys (Praomys coucha) exhibited a number of cytoplasmic vacuoles after conventional paraffin-embedding procedures. These vacuoles were strongly PAS-positive in cryostat sections. Ultra-structurally, they were double membrane-bound structures filled with myelin figures and acid phosphatase-positive electron-dense matrix. Immunofluorescent microscopy revealed that these structures contained GM2 ganglioside. Other tissues or organs were histologically normal. Mating experiments indicated that the ganglioside storage in MCC mastomys is inherited as an autosomal recessive trait.

Country
Spain
Keywords

Male, CDU::6 - Ciencias aplicadas::63 - Agricultura. Silvicultura. Zootecnia. Caza. Pesca::636 - Veterinaria. Explotación y cría de animales. Cría del ganado y de animales domésticos, Paraffin Embedding, G(M2) Ganglioside, Periodic Acid-Schiff Reaction, Kidney, Lysosome, Immunohistochemistry, Epithelium, Kidney Tubules, Proximal, Lysosomal Storage Diseases, Muridae, Microscopy, Electron, Microscopy, Fluorescence, Animals, Female, Glycolipids, :6 - Ciencias aplicadas::63 - Agricultura. Silvicultura. Zootecnia. Caza. Pesca::636 - Veterinaria. Explotación y cría de animales. Cría del ganado y de animales domésticos [CDU], Crosses, Genetic

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
6
Average
Average
Average
Green