It has been presented comparative studies of biopsies by means of two above mentioned probes in outpatients. It has been assessed the quality and quantity of obtained histopathological specimens and it has been compared relative pain perception during procedure among patients. Micro-curettage was performed twice in each woman. In the first group--the first curettage with Novak's probe and the second one the Pipelle's probe; in the second group--conversely. Aspirated endometrium was studied histopathologically. It has not been obtained specimen in 5 cases using Pipelle's probe that means in 20.83%; using Novak's probe in 25.0%. Microcuretage with Pipelle's probe was described as painless by 37.5% patients. The procedure with Novak's probe was always more or less painful. It has been found that both types of ++micro-curettage have the same effectiveness allowing to obtain histopathological specimens. It has been noticed that Pipelle's probe ensured higher comfort that means it has been more painless. It is a disposable probe giving full sterility of performing procedure.