Spontaneous thymoma in an inbred strain of rat.

descriptionPublicationkeyboard_double_arrow_right Article 29 Jul 1977 English Journal:Journal of the National Cancer Institute, volume 58 (issn: 0027-8874,

Authors: S M, Hinsull; D, Bellamy;

pmid: 864741

Spontaneous thymoma in an inbred strain of rat.

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Abstract

Thymomas that appear with high frequency in inbred WAB rats living into old age were examined. The spontaneous thymomas described were discrete, encapsulated bodies composed of lymphocytes and epithelial cells, with a predominance of lymphocytes. The rat neoplasms resembled the human thymomas, and their rate of incidence in older animals may suggest their use as models for the human condition.

Keywords

Male, Thymoma, Epithelial Cells, Rats, Inbred Strains, Thymus Neoplasms, Epithelium, Rats, Rodent Diseases, Disease Models, Animal, Animals, Female, Lymphocytes

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