The analysis of the influence of the drivers' health condition on the occurrence of traffic accidents was presented. The tested group consisted of 930 drivers with diseases or conditions that demanded the constant health control and monitoring. Control group was composed of 320 completely healthy drivers. Both groups were approximately similar in relation to the other factors that could influence the occurrence of traffic accidents. The behavior of these drivers was followed up in the four-years period. The results suggested that drivers with certain diseases and conditions, (psychological-psychiatric conditions and diseases, arterial hypertension, diabetes mellitus, hearing and sight impairments, varices cruris, stomach and duodenal ulcers) significantly more often cause the traffic accidents, compared to healthy drivers. The need for constant and rigorous health selection for drivers is imposed in order to alleviate the epidemic of traffic traumatism.