Are 5S ribosomal RNA primary transcripts edited?
Copyright policy )Are 5S ribosomal RNA primary transcripts edited?
Comparative analysis of the nucleotide sequences of plant 5S rRNA genes shows numerous discrepancies with the mature 5S rRNAs. Detailed inspection of these differences revealed that they are mainly due to single nucleotide substitutions, insertions and deletions. In several cases also longer insertions were found, two of which are particularly interesting. Their location in loops resembles tRNA introns. One of these insertions is 79 nucleotides long and can potentially form a tRNA-like structure, with 50% homology to plant tRNAGly. This observation led us to propose that, in the maturation of some 5S rDNA transcripts, editing and splicing mechanisms may be involved.
- Polish Academy of Learning Poland
Base Sequence, RNA Splicing, Sequence Homology, Nucleic Acid, Molecular Sequence Data, RNA, Ribosomal, 5S, Nucleic Acid Conformation, RNA Editing, Genes, Plant
Base Sequence, RNA Splicing, Sequence Homology, Nucleic Acid, Molecular Sequence Data, RNA, Ribosomal, 5S, Nucleic Acid Conformation, RNA Editing, Genes, Plant
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