In search of a cheaper and effective dressing solution for ulcers, 53 patients presenting with various types of ulcers at the University of Port Harcourt Teaching Hospital were treated with different strengths hypertonic saline 0.3, 0.9, 1.2, 1.5, 2 and 3 osmoles. The ages of the ulcers were between 3 months and 3 years. Optimal results were obtained with solution of 1.5 mmols and above. Desloughing occurred within 2 weeks and granulation was fast and good enough for skin grafting where necessary. Healing was faster in other ulcers that were not due for grafting.