Scabies is clearly the primary medical problem involving mites. However, regionally, there is a broad variety of other dermatoses associated with mite exposure, which in some areas vastly exceed the incidence of scabies. Also, scabies is characterized by a cyclical occurrence that is unusual in other mite infestations and mite-associated dermatoses. Many of these have seasonal or regional characteristics, which will be discussed. The clinical aspects of mite infestation will primarily be dealt with, and the basic anatomy and biology of the mites will be ignored.