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[Is risk-oriented therapy in stage I non-seminoma tumor advisable?].

Authors: S, Krege; H, Rübben;

[Is risk-oriented therapy in stage I non-seminoma tumor advisable?].

Abstract

For a long time the usual regimen for patients with a non-seminomatous testicular tumor, clinical stage I, was an orchiectomy and retroperitoneal lymphadenectomy. Because of the possible loss of ejaculation as a aggravating consequence for the patient, one must think about alternatives. One of those is the wait-and-see strategy. Recurrences, which occur in 30% of the patients, 15% retroperitoneal and 15% pulmonary, can be cured with chemotherapy. Unfortunately, the recurrence is often discovered late because the uncertainty of radiological diagnostic procedures. Then several courses of inductive chemotherapy are necessary. Thus, it is worthwhile to consider primary adjuvant chemotherapy. There have been only a few reports about this strategy, but all are very hopeful. The advantages and disadvantages of the different strategies are discussed in the following paper.

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Keywords

Male, Neoplasms, Germ Cell and Embryonal, Combined Modality Therapy, Testicular Neoplasms, Chemotherapy, Adjuvant, Risk Factors, Antineoplastic Combined Chemotherapy Protocols, Humans, Lymph Node Excision, Orchiectomy, Neoplasm Staging

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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