Medical technology must keep pace with the demands of health care to deliver cost-effective solutions. Automated test equipment can have an important role in medical technology just as it does in manufacturing test. The VXIbus architecture can field a wide range of instruments that could support many traditional biomedical instruments. For example, a patient monitoring system that possesses multiple channels of isolation, data acquisition, digital signal processing, storage, display, and networking could be integrated in a VXIbus system. Results could be displayed locally as well as networked as part of a larger hospital administration system. This article describes a project performed to demonstrate capabilities of VXIbus in biomedical applications. A simple temperature sensor is hosted on a B-size register based VXIbus card.