Patients with musculoskeletal disorders, including fibromyalgia syndrome (FS), often state that weather conditions modulate their complaints. There have been a few studies concerning this issue, but the results appear to be contradictory. We tried to relate the subjective symptoms of pain, stiffness, sleep and mood in patients with FS to objective meteorological factors. Correlation analyses showed no relation between the subjective complaints and the meteorological factors. The symptoms pain, stiffness and fatigue, however, showed a strong intercorrelation.