Several methods of facilitating the work schedule for in vitro fertilization programs have been proposed. LH-RH agonists offer the possibility of manipulating the day of hCG injection and consequently the day of ovum pick-up. Moreover, after desensitization, follicles are contemporarily stimulated and a higher number of mature oocytes are retrieved. The same objective of follicle synchronization can be obtained with progestins, which have the advantage of minor cost and less adverse effects. The use of oral contraceptives offers similar results to those obtained with progestins. The best choice in work programming appears to be a "monitorized programmed oocyte retrieval" with the use of progestins and LH-RH agonists.