[Comparison of the effect of sijunzi decoction, siwu decoction and bazhen decoction on immune function in mice].

A H, Xu; Y X, Gong; W R, Gu; X W, Wang

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China Journal of Chi...arrow_drop_down

China Journal of Chinese Materia Medica

Article . 1993

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[Comparison of the effect of sijunzi decoction, siwu decoction and bazhen decoction on immune function in mice].

descriptionPublicationkeyboard_double_arrow_right Article 16 Dec 1993Journal:Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, volume 18 (issn: 1001-5302,

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Authors: A H, Xu; Y X, Gong; W R, Gu; X W, Wang;

pmid: 8216794

[Comparison of the effect of sijunzi decoction, siwu decoction and bazhen decoction on immune function in mice].

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Abstract

Sijunzi decoction, Siwu decoction and Bazhen decoction can antagonize the suppressive effect of hydrocortisone on proliferation of lymphocyte by spleen cells in C57BL/6J mice in vitro, and of the three decoctions Sijunzi works best. Sijunzi Decoction can antagonize the suppressive effect of cyclophosphamide on the delayed cutaneous hypersensitivity (DCH) induced by DNCB in mice and the production of hemolysin in mice immunized with SRBC. The three prescriptions all can enhance the clearance rate of iv charcoal particles as well as bone marrow cells inhibited by cyclophosphamide in mice, but Sijunzi decoction functions best of all.

Keywords

Male, Metabolic Clearance Rate, Bone Marrow Cells, Cell Count, Hemolysin Proteins, Mice, Adjuvants, Immunologic, Charcoal, Animals, Female, Hypersensitivity, Delayed, Lymphocytes, Cell Division, Drugs, Chinese Herbal

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