Antitumor-promoting activity of mallotojaponin, a major constituent of pericarps of Mallotus japonicus.
Copyright policy Antitumor-promoting activity of mallotojaponin, a major constituent of pericarps of Mallotus japonicus.
Mallotojaponin, a major constituent of the pericarps of Mallotus japonicus (Euphorbiaceae), inhibited the action of tumor promoter in vitro and in vivo; it inhibited tumor promoter-enhanced phospholipid metabolism in cultured cells, and also suppressed the promoting effect of 12-O-tetradecanoylphorbol-13-acetate on skin tumor formation in mice initiated with 7,12-dimethylbenz-[a]anthracene.
Mice, Inbred ICR, Skin Neoplasms, Plant Extracts, 9,10-Dimethyl-1,2-benzanthracene, Phloroglucinol, Mice, Animals, Anticarcinogenic Agents, Humans, Tetradecanoylphorbol Acetate, Drug Interactions, Female, Phospholipids, HeLa Cells
Mice, Inbred ICR, Skin Neoplasms, Plant Extracts, 9,10-Dimethyl-1,2-benzanthracene, Phloroglucinol, Mice, Animals, Anticarcinogenic Agents, Humans, Tetradecanoylphorbol Acetate, Drug Interactions, Female, Phospholipids, HeLa Cells
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