
It is usually accepted that the phenomenon of thick filament shortening contradicts the sliding filament theory and cross-bridge mechanism of force generation. However, some peculiarity of experimental data indicate the thick filament shortening can be a corollary of the interaction of myosin cross-bridges with the actin filaments "wrong" polarities in sarcomeres with the actin filaments double overlap formed in the results of the filament sliding.
Muscles, Horseshoe Crabs, Animals, Actins
Muscles, Horseshoe Crabs, Animals, Actins
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