The authors describe a 35-year-old man who has had benign mucous membrane pemphigoid from the age of 12 years. Upper esophageal stricture, a rare complication of the syndrome, developed when he was 24 years old. This recurrent condition has been followed for 11 years. It was treated initially, for 6 years, with esophagoscopy and bougie dilatation. Balloon dilatation under fluoroscopic guidance was then substituted for bougienage; this procedure has been performed successfully 10 times over the last 5 years and remains the patient's preferred treatment. The mean period for recurrence of symptoms has been 5 months. Several previous reports of this condition describe treatment with esophagoscopy and bougie dilatation, but there has been no previous report of interventional radiology with balloon dilatation.