The effect of nasal decongestant on nasal mucous velocity.

K, Saketkhoo; B M, Yergin; A, Januszkiewicz; K, Kovitz; M A, Sackner

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American Review of R...arrow_drop_down

American Review of Respiratory Disease

Article . 1978

Data sources: Europe PubMed Central

The effect of nasal decongestant on nasal mucous velocity.

descriptionPublicationkeyboard_double_arrow_right Article 18 Nov 1978 English Journal:The American review of respiratory disease, volume 118 (issn: 0003-0805,

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Authors: K, Saketkhoo; B M, Yergin; A, Januszkiewicz; K, Kovitz; M A, Sackner;

pmid: 80967

The effect of nasal decongestant on nasal mucous velocity.

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Abstract

Nasal mucous velocity was measured in 13 healthy nonsmokers before and 10 min after topical application of 2 alpha adrenergic nasal decongestant sprays, phenylephrine and tetrahydrozoline. Phenylephrine increased nasal mucous velocity from 8.4 +/- 2.7 mm per min (mean +/- SD) to 13.7 +/- 4.8 mm per min and tetrahydrozoline from 8.1 +/- 3.8 mm per min (mean +/- SD) to 13.8 +/- 5.1 mm per min. These increases were significant (P less than 0.01) when compared to topical application of phenylephrine and tetrahydrozoline vehicles, normal saline, and sham (empty aerosol container).

Keywords

Adult, Aerosols, Male, Administration, Topical, Imidazoles, Middle Aged, Drug Combinations, Mucus, Nasal Decongestants, Nasal Mucosa, Phenylephrine, Humans, Female, Citrates, Hydrochloric Acid, Pharmaceutical Vehicles, Benzalkonium Compounds, Drug Packaging, Edetic Acid, Aged

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