The aim of the study was to determine the mortality rate of adolescents in Vojvodina and analyze the most common causes of their death. For the analysis we used the data from the Health Statistics Annual and from individual statistics reports. The observation period was between 1986 and 1988. The mean mortality rate of the adolescents in Vojvodina for that period was 6.7/100000. The leading cause of death (54.74%) was accidents (mostly traffic accidents), malignant diseases and finally cardiovascular diseases. The mortality rate was higher among older adolescents. It was 4 times higher in the outpatients compared to the inpatients and caused either by the severity of the injury and/or inadequately handled injuries. For the highest percentage of the accidents responsible were external factors among which risk behavior of the young played a significant role. The task of the society is to take appropriate measures which would reduce the role of the external factors as a cause of death.