Resistance to activated protein C activity of an anti-beta 2-glycoprotein I antibody in the presence of beta 2-glycoprotein I.
Copyright policy )Resistance to activated protein C activity of an anti-beta 2-glycoprotein I antibody in the presence of beta 2-glycoprotein I.
Some researchers claim that lupus anticoagulant-positive plasma may cause a false-positive reaction in the test for activated protein C (APC) resistance, a hereditary thrombophilic state characterized by abnormal factor V, which frequently causes venous thrombosis. We investigated whether anti-beta 2-glycoprotein I antibody (aGPI), which has recently come to be regarded as an anti-cardiolipin antibody (aCL) itself, might have an effect on the APC resistance test.
- Teikyo University Japan
beta 2-Glycoprotein I, Antibodies, Anticardiolipin, Immunoglobulin G, Dose-Response Relationship, Immunologic, Humans, False Positive Reactions, Thrombophlebitis, Blood Coagulation, Glycoproteins, Protein C
beta 2-Glycoprotein I, Antibodies, Anticardiolipin, Immunoglobulin G, Dose-Response Relationship, Immunologic, Humans, False Positive Reactions, Thrombophlebitis, Blood Coagulation, Glycoproteins, Protein C
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