
The reactivity of five monoclonal antibodies against ovarian carcinoma-associated antigens (OC125, OV632, OV-TL3, 8C, 10B) on tissue sections of malignant and benign ovarian neoplasms was estimated and compared using PAP technique. The immunodiagnostic usefulness of OC125 and OV-TL3 antibodies in differentiation between serous and endometrioid ovarian carcinomas was indicated. OV632 monoclonal antibody appears to be a good marker for differentiation between malignant and benign changes in ovary. Difficulties in typing of monoclonal antibodies for immunodiagnostic purposes were pointed out.
Diagnosis, Differential, Immunoenzyme Techniques, Ovarian Neoplasms, Antigens, Neoplasm, Carcinoma, Antibodies, Monoclonal, Humans, Female, Ovarian Diseases
Diagnosis, Differential, Immunoenzyme Techniques, Ovarian Neoplasms, Antigens, Neoplasm, Carcinoma, Antibodies, Monoclonal, Humans, Female, Ovarian Diseases
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