[Autoantibodies against podocytes of the kidney glomerulus].

Name: [Autoantibodies against podocytes of the kidney glomerulus].
Creator: W B, Storch
Keywords: Adult, Adolescent, Kidney Glomerulus, Fluorescent Antibody Technique, Humans, Middle Aged, 3. Good health, Autoantibodies

descriptionPublicationkeyboard_double_arrow_right Article 03 May 1995 German Journal:Immunitat und Infektion, volume 23

Authors: W B, Storch;

pmid: 7698810

[Autoantibodies against podocytes of the kidney glomerulus].

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Abstract

Novel autoantibodies are described which react with renal podocytes. These antibodies were found in 9 patients (2 with renal disease, 2 with liver disease, 2 with rheumatic disease, 1 with achalasia, 1 with carcinoma of the pancreas and 1 with anemia). Colocalization studies with double immunofluorescence and confocal laser scanning microscopy using monoclonal antibodies against the 44 kD podocyte protein showed a similar fluorescence pattern for both antibodies. The target antigens remain unclear.

Keywords

Adult, Adolescent, Kidney Glomerulus, Fluorescent Antibody Technique, Humans, Middle Aged, Autoantibodies

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