[The effects of mexidol in pain syndromes].
Copyright policy )[The effects of mexidol in pain syndromes].
Models of neuropathic pain syndrome and adjuvant arthritis were used to study the effect of mexidole, an antioxidant from the 3-hydroxypyridine group. Mexidole was indicated to produce no preventive effect in pain syndromes, but to exhibit a therapeutic one. The use of mexidole in combination with the agents activating the monoaminergic systems in the central nervous system showed the presence of their reciprocal effect in neuropathic pain syndrome and its absence in adjuvant arthritis. Possible mechanisms of action of mexidole were also discussed.
Pain Threshold, Hot Temperature, Time Factors, Drug Evaluation, Preclinical, Pain, Syndrome, Arthritis, Experimental, Antioxidants, Rats, Disease Models, Animal, Picolines, Animals, Drug Interactions, Drug Therapy, Combination
Pain Threshold, Hot Temperature, Time Factors, Drug Evaluation, Preclinical, Pain, Syndrome, Arthritis, Experimental, Antioxidants, Rats, Disease Models, Animal, Picolines, Animals, Drug Interactions, Drug Therapy, Combination
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!