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Folia Biologica
Article . 1995
Data sources: Europe PubMed Central
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From clones of cells to clones of genes.

descriptionPublicationkeyboard_double_arrow_right Article 07 Dec 1995 English Journal:Folia biologica, volume 40 (issn: 0015-5500, Copyright policy )
Authors: I, Lefkovits;

pmid: 7589699

From clones of cells to clones of genes.

Abstract

Three approaches to study the immune system are presented. First is the limiting dilution analysis, second is the analysis of the polypeptide patterns of lymphocytes by two-dimensional gel electrophoresis, and the third is the utilization of a partitioned cDNA library for establishing a gene catalog and proteinpaedia. All the approaches were used to study clonal diversity and clonal heterogeneity. The gene catalog which is already established is available to recover genes expressed in various lymphocyte clones.

Keywords

B-Lymphocytes, DNA, Complementary, Lymphocyte Activation, Models, Biological, Clone Cells, Mice, Animals, Humans, Lymphocytes, Poisson Distribution, RNA, Messenger, Cloning, Molecular, Cell Division, Spleen, Gene Library

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    popularity
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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
gold