Antibodies to bacterial L-asparaginases.

Complement fixation has been shown to occur when asparaginase reacts with specific antibody. This is as a result of an antigenic determinant common to the four bacterial asparaginases. Patients on asparaginase therapy may produce antibodies and these could be demonstrated by complement fixation.

Keywords

Adult, Male, Adolescent, Chromobacterium, Complement Fixation Tests, Cross Reactions, Middle Aged, Antibodies, Epitopes, Enterobacteriaceae, Asparaginase, Humans, Female

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