[Water channel family proteins].
Copyright policy )[Water channel family proteins].
17 members of MIP family from bacteria, yeast, plants and animals are compared in this review. These proteins appear to function in (1) water channels (CHIP, WCH-CD, MIWC, AQP3, gTIP, RD28, TobRB7), (2) neurogenesis (Bib), (3) small-molecule-permeating channels (MIP, AQP3, NOD, Glpf), (4) unknown function (WCH-3, AtRB7, Pea R7A, FPS1). However, the biological functions are not well established. The most conserved residues in the first and the second halves of all MIP family proteins are asparagine-proline-alanine (NPA) sequences in the loops (NPA boxes). This structural similarity may lead to functional similarity (water and/or small molecule permeation). This signature sequence for the MIP family will facilitate the identification of new protein members of this family.
Fungal Proteins, Cell Membrane Permeability, Bacterial Proteins, Molecular Sequence Data, Animals, Membrane Proteins, Amino Acid Sequence, Ion Channels, Plant Proteins
Fungal Proteins, Cell Membrane Permeability, Bacterial Proteins, Molecular Sequence Data, Animals, Membrane Proteins, Amino Acid Sequence, Ion Channels, Plant Proteins
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Citations provided by BIP!Popularity provided by BIP!