[LDL-receptor-related protein].
Copyright policy )[LDL-receptor-related protein].
The LDL-receptor-related protein is a multifunctional endocytotic receptor that clear apo E- and/or lipoprotein lipase-enriched lipoproteins, proteases such as alpha 2-macroglobulin plasminogen and activator inhibitor-1 (PAI-1), Pseudomonas exotoxin A and probably vitellogenin from blood circulation. Its role in plasma chylomicron remnant clearance has been postulated, and recently has been demonstrated by using its inhibitor; receptor-associated protein (RAP) in LDL receptor knockout mice.
- University of Tokyo Japan
Lipoproteins, Exotoxins, Mice, Vitellogenins, Plasminogen Activator Inhibitor 1, Animals, Humans, alpha-Macroglobulins, Receptors, Immunologic, Low Density Lipoprotein Receptor-Related Protein-1, Protein Binding
Lipoproteins, Exotoxins, Mice, Vitellogenins, Plasminogen Activator Inhibitor 1, Animals, Humans, alpha-Macroglobulins, Receptors, Immunologic, Low Density Lipoprotein Receptor-Related Protein-1, Protein Binding
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