Contralateral rotations induced by intrastriatal injections of agonists of excitatory amino acid receptors.
Copyright policy )Contralateral rotations induced by intrastriatal injections of agonists of excitatory amino acid receptors.
NMDA (100, 250 and 500 ng/0.5 microliters), kainic acid (50 and 100 ng/0.5 microliters) and AMPA (500 and 1000 ng/0.5 microliters), injected unilaterally into the ventrolateral part of the intermediate region of the caudate-putamen of rats, induced contralateral rotations. It is proposed that stimulation of NMDA, kainate and AMPA receptors present on strionigral neurons evokes an "antiparkinsonian effect".
Male, Kainic Acid, N-Methylaspartate, Behavior, Animal, Kainic Acid Receptors, Receptors, N-Methyl-D-Aspartate, Rats, Animals, Receptors, AMPA, Rats, Wistar, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, Injections, Intraventricular
Male, Kainic Acid, N-Methylaspartate, Behavior, Animal, Kainic Acid Receptors, Receptors, N-Methyl-D-Aspartate, Rats, Animals, Receptors, AMPA, Rats, Wistar, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, Injections, Intraventricular
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