
A pattern of nerve stimulation called train-of-four (TOF) is frequently used to monitor therapy with nondepolarizing neuromuscular blocking agents in patients treated in intensive care units. Based on our experience with TOF monitoring in several critically ill patients, we believe its application as an indicator of neuromuscular blockade may be problematic in this setting.
Intensive Care Units, Critical Illness, Neuromuscular Depolarizing Agents, Neuromuscular Junction, Humans, Peripheral Nerves, Drug Monitoring, Electric Stimulation, Neuromuscular Nondepolarizing Agents
Intensive Care Units, Critical Illness, Neuromuscular Depolarizing Agents, Neuromuscular Junction, Humans, Peripheral Nerves, Drug Monitoring, Electric Stimulation, Neuromuscular Nondepolarizing Agents
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