
Magnetic resonance urography (MRU) after i.v. injection of gadolinium-DTPA (0.1 mmol/kg bodyweight) was performed in a patient with transplant dysfunction after renal allograft transplantation. Renal replacement therapy was accomplished by means of peritoneal dialysis. Gadolinium-DTPA concentrations in urine and dialysate were measured repeatedly during a 48-h period with inductively coupled plasma atomic emission spectrometry. The total 24-h creatinine clearance was 10.8 ml/min on day 1 and 13.7 ml/min on day 2. The corresponding total gadolinium clearance was 12.8 ml/min and 15.8 ml/min respectively. Gadolinium-DTPA was removed from the body through peritoneal dialysis at a mean clearance rate of 5.13 ml/min. Plasma half-life of gadolinium-DTPA was prolonged to 9 h. No side-effects due to gadolinium-DTPA were noted. MRU provided a better visualization of the morphology of the urinary tract than scintigraphic studies. By measuring the changes of signal intensity, the gadolinium excretion could be calculated.
Adult, Gadolinium DTPA, Male, Contrast Media, Urography, Pentetic Acid, Kidney, Magnetic Resonance Imaging, Organometallic Compounds, Humans, Peritoneum, Peritoneal Dialysis, Half-Life
Adult, Gadolinium DTPA, Male, Contrast Media, Urography, Pentetic Acid, Kidney, Magnetic Resonance Imaging, Organometallic Compounds, Humans, Peritoneum, Peritoneal Dialysis, Half-Life
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